The Super Eagles winger had a knock before the international break and has since been unavailable for both club and country, missing Saturday’s loss to Crystal Palace.
Pedro is expected to deputise at wing-back but Antonio Conte will monitor the Nigerian’s condition.
Chelsea are seven points clear of second-placed Spurs ahead of the Manchester city game, but will do everything to put behind the shock defeat they suffered at home to Crystal Palace last weekend.
Conte seems cautious but ready for another tough test. “We are in a really good position,” said. “We haven’t had many days to prepare for this game but it’s the same for Man City. These teams have a clear identity.
“It won’t be easy because they are a very good team.”